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EPSRC Support by Research Area in Chemical Biology and Biological Chemistry

Research areas are used to describe EPSRC's portfolio of excellent long term research and high quality postgraduate training.

Grants are classified using one or more research areas. All the grants listed below have some relevance to this research area. The value of the investment is the total awarded by EPSRC and does not reflect the proportion assigned to this research area.

We always try to ensure that grants on the web contains the most recent information but it is possible that some might be slightly out of date.

Grant TitlePrincipal
Investigator
OrganisationDepartmentTotal Grant
Value (£)
A Coordinated Infrastructure for NMR for the Physical and Life Sciences: Upgrade to the Ultra-high Field 950 MHz Spectrometer at OxfordRedfield, Professor CUniversity of OxfordBiochemistry 477,380
A Coordinated Infrastructure for NMR in the Physical and Life Sciences: A 1 GHz Spectrometer at BirminghamGunther, Professor ULUniversity of BirminghamInstitute of Cancer and Genomic Sciences 6,558,752
A Coordinated Infrastructure for NMR in the Physical and Life Sciences: Upgrade of the Leicester 800MHz NMR for Structural Biology and Drug DiscoveryVuister, Professor G WUniversity of LeicesterMolecular and Cell Biology 928,156
A National Network for Applications of High-Field NMR in the Life and Physical SciencesUhrin, Professor DUniversity of EdinburghSch of Chemistry 1,368,030
A new tool to support drug discovery: Native LESA mass spectrometry (NESA)Cooper, Professor HJUniversity of BirminghamSch of Biosciences 411,030
A World-Leading National Network for NMR in the Physical and Life Science: Very-High Field Infrastructure at SheffieldWilliamson, Professor MUniversity of SheffieldMolecular Biology and Biotechnology 844,525
An EPSRC National Research Facility to facilitate Data Science in the Physical Sciences: The Physical Sciences Data science Service (PSDS)Coles, Professor SJUniversity of SouthamptonSchool of Chemistry 2,996,067
Autonomous Discovery of Functional Small MoleculesNelson, Professor ASUniversity of LeedsSch of Chemistry 1,245,808
Bioorthogonal Gold Chemistry to Explore Novel Biomedical ApplicationsUnciti-Broceta, Dr AUniversity of EdinburghEdinburgh Cancer Research Centre 513,211
Cloud-based methods to predict the druggability of protein-protein interactions: applications to cancer and antimicrobial resistance.Laughton, Professor CUniversity of NottinghamSch of Pharmacy 293,994
Cobalt- and Nickel-based Polymetallocenes: Functional Metallopolymers from Earth-Abundant MetalsO'Hare, Professor DUniversity of OxfordOxford Chemistry 19,612
Controlling Membrane Translocation for Artificial Signal TransductionHunter, Professor CAUniversity of CambridgeChemistry 405,953
Controlling membrane translocation for artificial signal transductionWilliams, Professor NHUniversity of SheffieldChemistry 356,411
Cross-scale prediction of Antimicrobial Resistance: from molecules to populations.Keeling, Professor MUniversity of WarwickMathematics 501,448
Designer Chemistry to Probe Supramolecular Assembly Mechanism and FunctionWilson, Professor AJUniversity of LeedsSch of Chemistry 458,233
Dinuclear ruthenium light-switches as multi-output sub-cellular imaging probes within live cells and tissuesThomas, Professor JAUniversity of SheffieldChemistry 711,979
Diversity-Oriented Synthesis of Stapled PeptidesSpring, Professor DUniversity of CambridgeChemistry 1,205,345
Efficient modelling and validation of cryptic protein binding sites for drug discoveryMichel, Dr JUniversity of EdinburghSch of Chemistry 198,251
Efficient modelling and validation of cryptic protein binding sites for drug discoveryGervasio, Professor FUCLChemistry 272,316
Enabling ultra-high resolution hydrogen/deuterium exchange for challenging biomedical systemsZhuravleva, Dr AUniversity of LeedsAstbury Centre 100,792
Enhancing 800 MHz NMR Capabilities at NottinghamSearle, Professor MUniversity of NottinghamSch of Chemistry 965,910
Enzymatic tools for biotechnology and medicineNeely, Dr RKUniversity of BirminghamSchool of Chemistry 1,000,807
EPSRC and MRC Centre for Doctoral Training in Systems Approaches to Biomedical ScienceDeane, Professor CUniversity of OxfordMathematical, Physical&Life Sciences Div 3,552,982
EPSRC Centre for Doctoral Training in Physical Sciences for Health (Sci-Phy-4-Health)Hannon, Professor MJUniversity of BirminghamSchool of Chemistry 3,509,930
EPSRC Centre for Doctoral Training in Physical Sciences Innovation in Chemical Biology for Bioindustry and HealthcareCes, Professor OImperial College LondonDept of Chemistry 4,617,554
EPSRC Centre for Doctoral Training in Synthesis for Biology and MedicineDixon, Professor DJUniversity of OxfordOxford Chemistry 4,812,102
EPSRC Flagship Software - BioSimSpace: A shared space for the community development of biomolecular simulation workflowsMichel, Dr JUniversity of EdinburghSch of Chemistry 523,963
EPSRC IRC Proteus - Multiplexed 'Touch and Tell' Optical Molecular Sensing and Imaging - Lifetime and BeyondBradley, Professor MUniversity of EdinburghSch of Chemistry 3,852,992
EPSRC UK National Crystallography ServiceColes, Simon JohnUniversity of SouthamptonSchool of Chemistry 4,680,553
Establishing a Design Blueprint for Nanomedicines for Oral Drug DeliveryVllasaliu, Dr DKings College LondonPharmaceutical Sciences 82,118
Establishing an Approach for the Selection and Design of Secondary Structure Mimetics to Antagonise Protein-protein Interactions.Mason, Dr JMUniversity of BathBiology and Biochemistry 26,426
Evaluation of Potential of Zwitterionic Salts for the Development of Protein-Resistant SurfacesBlesic, Dr MQueen's University of BelfastSch of Chemistry and Chemical Eng 110,174
Expanding the biochemical toolbox for protein modification at cysteineMacmillan, Dr DUCLChemistry 375,298
FINESSE NanoBio (Fabrication and Imaging of Neon-Etched Structures and Surfaces for Engineering, Nanoscience and Biotechnology)Daly, Dr RUniversity of CambridgeEngineering 2,427,240
Fluorovinyl thioethers as stereoelectronic mimetics of acyl co-enzyme-A enol/atesO'Hagan, Professor DUniversity of St AndrewsChemistry 400,859
High Resolution Solid State Nitrogen-14 NMRCarravetta, Dr MUniversity of SouthamptonSchool of Chemistry 489,366
Hydrophobic Gating in Membrane Nanopores: Water at the NanoscaleSansom, Professor MUniversity of OxfordBiochemistry 379,691
Identification and nucleotide resolution mapping of alkyl adducts in human DNAPovey, Dr AndrewUniversity of Manchester, TheSchool of Medical Sciences 169,254
Immuno-chemotherapeutic Metal Complexes for Cancer Stem Cell-Directed TherapySuntharalingam, Dr KKings College LondonChemistry 217,731
Injectable devices for sustained ocular drug deliveryKearns, Dr VRUniversity of LiverpoolInstitute of Ageing and Chronic Disease 838,666
Integrated computational and synthetic tools to drive the discovery of orthosteric protein-protein interaction inhibitorsWilson, Professor AJUniversity of LeedsSch of Chemistry 2,751,527
Ion Beam Analysis for the 2020's and Beyond: An Integration of Elemental Mapping and 'omics'Bailey, Dr MJUniversity of SurreyChemistry 1,025,483
Lanthanide complexes as chiral probes and labelsParker, Professor DDurham, University ofChemistry 582,868
LCVD: Low-cost Cell-extract Viral DiagnosticsAjioka, Dr JWUniversity of CambridgePathology 1,541,002
Metal-free couplings for molecules, materials and bioactive targetsProcter, Professor DJUniversity of Manchester, TheChemistry 1,146,757
Mimetic sugar nucleotides to probe a strategic bacterial dehydrogenase enzymeMiller, Dr GJKeele UniversityFaculty of Natural Sciences 245,957
Minimal DNA Nanopores for Electrical Sensing of ProteinsHoworka, Dr SUCLChemistry 405,368
Modify-catch-release-repeat: Reversible bioconjugations for controlled release of small molecules from antibodies and their fragmentsFascione, Dr M AUniversity of YorkChemistry 397,840
Molecular Switches as Sensors for Kinase ActivityThomson, Dr AUniversity of GlasgowSchool of Chemistry 98,151
Nanoanalysis for Advanced Materials and HealthcareMartin, Professor RWUniversity of StrathclydePhysics 13,061
Nanoscale metallomics and mineralization: advanced spectro-microscopy determination of the role of iron and calcium in Alzheimer's diseaseCollingwood, Dr JFUniversity of WarwickSch of Engineering 418,210
Nanoscale metallomics and mineralization: advanced spectro-microscopy determination of the role of iron and calcium in Alzheimer's diseaseTelling, Professor NDKeele UniversityInst for Science and Tech in Medicine 337,549
New Directions in Bioisostere ResearchAnderson, Professor EAUniversity of OxfordOxford Chemistry 572,768
Nicotinic Ligand Development to Target Smoking Cessation and Gain a Molecular Level Understanding of Partial AgonismGallagher, Professor TUniversity of BristolChemistry 724,553
One size fits all: The semi-synthesis of new undecaprenol analogues for the study of multiple undecaprenyl-processing enzymesCochrane, Dr SQueen's University of BelfastSch of Chemistry and Chemical Eng 215,788
Orthogonal Modules Engineered for Synthetic Protein- and Microbial-NetworksHowarth, Professor MRUniversity of OxfordBiochemistry 372,234
Palladium-activated prodrug therapy: a novel focal therapy for localised cancers of unmet needUnciti-Broceta, Dr AUniversity of EdinburghEdinburgh Cancer Research Centre 1,074,212
Partially fluorinated alkyl motifs for pharmaceuticals and agrochemicals researchO'Hagan, Professor DUniversity of St AndrewsChemistry 424,425
PET Markers of Oligomeric Misfolded Proteins in Neurodegenerative DisordersAigbirhio, Professor FIUniversity of CambridgeWolfson Brain Imaging Centre 1,041,821
Poised Fragment Libraries for Atypical Bromodomain InhibitionSpencer, Professor JUniversity of SussexSch of Life Sciences 428,829
Predicting drug-target binding kinetics through multiscale simulationsMulholland, Professor AJUniversity of BristolChemistry 225,397
Profiling the „Methylome? Targets of the Histone Lysine Methyltransferases: DOT1LFuchter, Dr MatthewImperial College LondonDept of Chemistry 283,026
Property-Enhanced PorphyrinsChauvet, Dr A A PUniversity of SheffieldChemistry 379,306
Radiotherapy activated materials for enhanced cancer treatmentsAlexander, Professor CUniversity of NottinghamSch of Pharmacy 539,154
Raman Spectroscopy of Live Cell Invasion of 3D nano-fabricated scaffoldsAshton, Dr LLancaster UniversityChemistry 89,758
Sensors for clean water: a participatory approach for technology innovationJohnson, Dr SDUniversity of YorkElectronics 1,182,012
Singlet Fission in Carotenoid Aggregates (SIFICA)Clark, Dr JUniversity of SheffieldPhysics and Astronomy 851,312
Singlet Fission in Carotenoid Aggregates (SIFICA)Barford, Professor WUniversity of OxfordOxford Chemistry 294,636
Site-selective antibody modification by cysteine-to-lysine transfer (CLT)Baker, Dr JRUCLChemistry 411,777
Software for experimentally driven macromolecular modellingDegiacomi, Dr MDurham, University ofChemistry 687,453
Solid-State NMR at 1.0 GHz: A World-Leading UK Facility to Deliver Advances in Chemistry, Biology and Materials ScienceBrown, Professor SPUniversity of WarwickPhysics 7,889,144
Structural dynamics and photoinduced electron transferVlcek, Professor AQueen Mary University of LondonSch of Biological and Chemical Sciences 649,756
Structural Dynamics in LOV Domain Photosensor ProteinsMeech, Professor SUniversity of East AngliaChemistry 352,953
Substrate Peptidomimetic Inhibitors (SPIs) of the COP9 signalosomeJamieson, Dr AUniversity of GlasgowSchool of Chemistry 189,897
Substrate Peptidomimetic Inhibitors (SPIs) of the COP9 signalosomeKessler, Dr BMUniversity of OxfordTarget Discovery Institute 116,018
Switching On and Powering Molecular Machines: Ultrafast Dynamics of PhotoswitchesMeech, Professor SUniversity of East AngliaChemistry 362,388
Synthesis and Biology of ProstanoidsAggarwal, Professor VKUniversity of BristolChemistry 1,061,277
Synthesis and characterisation of DNA adducts derived from the bracken toxin ptaquiloside.Williams, Dr DUniversity of SheffieldChemistry 354,312
Synthesis of the RNA polymerase inhibitor tagetitoxinPorter, Dr MJUCLChemistry 389,768
Tetra-(Polyfluoroaryl)-Porphyrin Templated Multicyclic Peptides: Novel, Functional and Responsive Scaffolds for Miniaturised BiosensorsCoxon, Dr CRLiverpool John Moores UniversityPharmacy and Biomolecular Sciences 100,602
The quantitative analysis of signalling dynamics in breast cancer : an interdisciplinary approachBaum, Dr BuzzUCLMRC Laboratory of Molecular Cell Biology 327,905
The Realisation of Fragment-Oriented SynthesisMarsden, Professor SPUniversity of LeedsSch of Chemistry 574,490
The UK High-End Computing Consortium for Biomolecular SimulationMulholland, Professor AJUniversity of BristolChemistry 288,481
The UK High-End Computing Consortium for Biomolecular SimulationKhalid, Professor SUniversity of SouthamptonSchool of Chemistry 321,432
Triple Imaging with PARASHIFT ProbesParker, Professor DDurham, University ofChemistry 370,028
Triple Imaging with PARASHIFT ProbesBlamire, Professor AMNewcastle UniversityInstitute of Cellular Medicine 238,021
Very-High Field NMR in the Physical and Life Sciences at the University of LiverpoolBlanc, Dr FUniversity of LiverpoolChemistry 1,277,656
Wellcome EPSRC Centre for Medical EngineeringRazavi, Professor RSKings College LondonImaging & Biomedical Engineering 6,165,151

Total Number of Grants: 88
Total Value of Grants: £92,692,422

The grant value may include the cost of access to facilities (these funds are not awarded to the grant holding organisation).