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Details of Grant 

EPSRC Reference: GR/M91655/01
Title: (JREI) MICRO-THERMAL MICROSCOPY AND ANALYSIS
Principal Investigator: Pollock, Dr H
Other Investigators:
Krier, Professor A Hetherington, Professor AM Rimmer, Professor S
Jones, Dr B Fullwood, Dr NJ Allsop, Professor D
Researcher Co-Investigators:
Project Partners:
Thermomicroscopes
Department: Physics
Organisation: Lancaster University
Scheme: JREI
Starts: 31 August 2000 Ends: 30 August 2003 Value (£): 104,470
EPSRC Research Topic Classifications:
Biological & Medicinal Chem. Condensed Matter Physics
Design & Testing Technology
EPSRC Industrial Sector Classifications:
Chemicals Electronics
Pharmaceuticals and Biotechnology No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
At Lancaster University, new varieties of scanning probe microscopy have been pioneered and combined with analytical techniques such as thermal analysis. Collaboration between physicists, chemists and biologists has enabled us to undertake a number of current funded projects. However, our existing instruments are heavily overloaded, being used in addition for continuing instrumental development work. We now seek funding for two further instruments which would complete the infrastructure needed to support dedicated work on future specific research projects. These would include:(a) atomic force microscope (AFM) studies of amyloid fibrils, protofibrils and inhibitors of amyloid aggregation;(b) the use of affinity imaging and micro-thermal analysis to study bioadhesion and biofouling interactions;(c) scanning thermal microscopy and Infra-red Spectroscopy with Scanning Microscopy for work on metabolic activity of individual plant cells; and (d) on electromigation studies; and(e) AFM studies of semiconductor quantum dots, for LEDs and diode lasers.
Key Findings
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Potential use in non-academic contexts
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Impacts
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Summary
Date Materialised
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Further Information:  
Organisation Website: http://www.lancs.ac.uk