| EPSRC Reference: |
GR/R28911/01 |
| Title: |
Support and Enhancement For X-Ray Microtomography Faclity For Study Bone, Tooth and Engineering Materials |
| Principal Investigator: |
Elliott, Professor JC |
| Other Investigators: |
| Dowker, Dr SEP |
Wilkinson, Professor AJ |
Hing, Dr K |
| Mummery, Dr P |
Davis, Professor GR |
Wong, Professor F |
| Goodship, Professor A |
Boyde, Professor A |
Tanner, Professor KE |
| Lee, Professor P |
Mummery, Professor P |
Zioupos, Professor P |
| Anderson, Professor P |
Samarawickrama, Dr D |
Taylor, Professor M |
| Derby, Professor B |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Medicine & Dentistry |
| Organisation: |
Queen Mary University of London |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 July 2001 |
Ends: |
31 December 2004 |
Value (£): |
154,327
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| EPSRC Research Topic Classifications: |
| Biomaterials |
Instrumentation Eng. & Dev. |
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| EPSRC Industrial Sector Classifications: |
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| Related Grants: |
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| Panel History: |
| Panel Date | Panel Name | Outcome |
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12 Mar 2001
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Metrology For Life Sciences
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Deferred
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Summary on Grant Application Form |
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A 3-dimensional X-ray microtomographic microscope facility will be established and used in a wide range of multidisciplinary studies of bones, teeth, and engineering materials. This form of microscopy is nondestructive and is a miniaturised form of the well-known medical CT scanner. It will give the required detail in 3-dimensions to a resolution of 5 microns for specimens with maximum dimensions of 50mm diameter by 60mm long. For many of the studies, changes in 3D structure wilt be recorded whilst the specimen is subjected to an applied load, or change in humidity, liquid environment or temperature. Both the static and dynamic observations will give detailed information about the specimen that cannot be obtained by any other methods. The dental studies will be relevant to the physicochemical mechanisms, diagnosis and treatment of caries, an extremely prevalent disease that is a major cost to the country. The micromechanical and microstructural studies of bone and bone implants will be used to futher understanding of bone in degenerative diseases of the skeleton (osteoporosis and osteoarthritis) with the aim of improving diagnosis and treatment. These diseases are costly and cause great distress to patients, for example, one in three women and one in twelve men suffer from osteoporosis and a high proportion of these individuals sustain fractures. Investigations of the engineering materials will focus on the fundamental relationships beween microstructure, deformation processes and mechanical properties of alloys, inorganic foams and composites.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
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