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Details of Grant 

EPSRC Reference: GR/M73057/01
Title: LABORATORY-ON-A-CHIP
Principal Investigator: Fielden, Professor PR
Other Investigators:
Goddard, Professor N
Researcher Co-Investigators:
Project Partners:
LGC Ltd-Laboratory of Government Chemist
Department: Instrumentation & Analytical Science
Organisation: UMIST
Scheme: Standard Research (Pre-FEC)
Starts: 01 March 1999 Ends: 30 September 2002 Value (£): 224,636
EPSRC Research Topic Classifications:
Analytical Science
EPSRC Industrial Sector Classifications:
Manufacturing Chemicals
Electronics Pharmaceuticals and Biotechnology
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
The proposed work based at UMIST will be integrated into the global objectives of the Laboratory-on-a-Chip consortium. The particular contribution of UMIST will be the development of generic integrated detection technology that may be adapted to match individual device needs for both microanalytical and microsynthetic systems. Key issues will include consideration of the techniques of: Optical absorbance, fluorescence and refractive index; and Electrochemical conductivity and voltammetric detection. The other primary criteria will include: square-section channel geometry (width and depth); sensitivity; signal-to-noise; spatial and temporal resolution; reproducibility with respect to geometric and materials stability; and the effect of applied electric fields (electrochemical measurements). Models will be developed to describe the design parameters for optical wave-guide based detectors, and microband electrochemical detectors. Optimised demonstrators will be constructed as proof-of-concept systems in collaboration with the consortium industrial partners.
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