Details of Grant 

EPSRC Reference:	GR/M52533/01
Title:	DEVELOPMENT OF A NOVEL METHOD OF ULTRA-FAST MAGNETIC RESONANCE IMAGING FOR QUANTITATIVE IMAGING OF TUMOURS
Principal Investigator:	Leach, Professor MO
Other Investigators:	Padhani, Dr A Bifone, Dr A Padhani, Dr A Doran, Dr SJ Collins, Mr D Rowland, Dr I Doran, Professor D
Researcher Co-Investigators:
Project Partners:
Department:	Division of Radiotherapy and Imaging
Organisation:	Institute of Cancer Research
Scheme:	Standard Research (Pre-FEC)
Starts:	15 November 1999	Ends:	14 November 2002	Value (£):	152,263
EPSRC Research Topic Classifications:	Image & Vision Computing
EPSRC Industrial Sector Classifications:	Healthcare No relevance to Underpinning Sectors
Related Grants:
Panel History:
Summary on Grant Application Form
Although it is now possible to cure a considerable fraction of all cancer patients, it is still often difficult to predict the outcome of radio-or chemotherapy and hence tailor treatment for an individual. One factor known to be important is the set of physical and structural properties that comprise a tumour's micro-environment . Magnetic Resonance Imaging (MRI) has already demonstrated great potential for investigating non-invasively many of the components of this micro-environment, but in order to maximise the information obtained from such studies, it is necessary to increase the speed of MRI measurements. In a collaboration between two institutions and five different disciplines, the applicants seek to address these issues by exploiting a new ultra-fast imaging technique called Burst, which has a number of extremely attractive properties. The goal of this project is to develop improved Burst pulse sequences, yielding higher resolution images with better signal-to-noise than currently available. Work will be performed on a 1.5 T clinical scanner, leading to patient trials, and on a new 11.7 T research system. In both cases, the ultra-fast images obtained will be used to measure quantitatively key parameters of the tumour micro-environment.
Key Findings
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Potential use in non-academic contexts
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Organisation Website:	http://www.icr.ac.uk