| EPSRC Reference: |
GR/L52932/01 |
| Title: |
A NEW HIGH FIELD NMR FACILITY TO SUPPORT UCL CHEMISTRY |
| Principal Investigator: |
Motherwell, Professor WB |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
UCL |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 April 1998 |
Ends: |
31 March 2001 |
Value (£): |
199,088
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| EPSRC Research Topic Classifications: |
| Biological & Medicinal Chem. |
Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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This proposal requests funding for a high-field NMR Spectrometer to support a large number of research programmes at UCL. For example, We will utilise high field NMR measurements to help us1. complete the first total synthesis of antitumour antibiotics A83586C and Citropeptin.2. Define the role played by the oligosaccaride regions of anthracycline antibiotics in their sequence selective binding to DNA.3. Elucidate the structures of chiral enolates in solution.4. Document new aspects of molecular conformation and clarify a range of existing poorly understood phenomena.5. Explore a new polarity-reversed catalytic method for performing the radical mediated asymmetric Aldol reaction.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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