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Details of Grant 

EPSRC Reference: EP/W030411/1
Title: MRtrix: enabling advanced tractography and microstructure analysis of diffusion MRI in the brain
Principal Investigator: Tournier, Dr J
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Florey Institute of Neuroscience and Men University of Antwerp University of Leuven
Department: Imaging & Biomedical Engineering
Organisation: Kings College London
Scheme: Standard Research
Starts: 01 April 2023 Ends: 31 March 2026 Value (£): 455,735
EPSRC Research Topic Classifications:
Medical Imaging Systems neuroscience
EPSRC Industrial Sector Classifications:
Related Grants:
Panel History:
Panel DatePanel NameOutcome
01 Mar 2022 Software for Research Communities Full Proposal Prioritisation Panel Announced
23 Nov 2021 Software for Research Communities Sift Panel 1 Announced
Summary on Grant Application Form
MRtrix is an open-source software project to provide high-quality implementations of novel and important technical innovations in the field of diffusion MRI analysis. Diffusion MRI is increasingly used to identify and study brain white matter fibre tracts and to investigate brain connectivity. MRtrix is a valuable software tool used by researchers in medical image processing and visualisation, neuroscience and neurotechnology and is already in use in at least 60 medical centres worldwide, and several commercial products.

MRtrix has so far been maintained by a small team of dedicated academics. However, the success of the project and its widespread adoption now makes it impossible for the team to maintain and enhance the project to the expected standard due to time constraints. The long-term sustainability of the project will require the active participation of a wider range of developers and maintainers, and support from an active community of knowledgeable users.

The aims of this project are therefore four-fold:

- to implement important features that will enable use of the software in a greater range of situations, improve interoperation with other complementary software packages, and ensure MRtrix is ready for future applications.

- to encourage researchers and developers to use MRtrix as the basis for the development and/or dissemination of their own methods (by improving the code documentation, providing online courses and articles, and providing rapid and responsive support);

- to maintain the software, fix outstanding issues, and ease the various processes involved as much as possible.

- to maximise user engagement and participation (by running workshops, providing online tutorials, and improving the documentation);

This project will fund a Research Software Engineer for 3 years to achieve these objectives.

Key Findings
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Potential use in non-academic contexts
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Date Materialised
Sectors submitted by the Researcher
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