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Details of Grant 

EPSRC Reference: EP/N026985/1
Title: Closed loop control systems for optimisation of treatment
Principal Investigator: Morgan, Professor SP
Other Investigators:
Hardman, Professor JG Byrne, Professor H Bates, Professor D
Korposh, Dr S
Researcher Co-Investigators:
Project Partners:
Department: Faculty of Engineering
Organisation: University of Nottingham
Scheme: Standard Research - NR1
Starts: 29 October 2016 Ends: 28 October 2019 Value (£): 634,068
EPSRC Research Topic Classifications:
Drug Formulation & Delivery Med.Instrument.Device& Equip.
Medical Imaging
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:
Panel DatePanel NameOutcome
26 Jan 2016 HT Networks Plus Panel Announced
23 Feb 2016 HT NetworksPlus Interviews Announced
Summary on Grant Application Form
A treatment that is optimised and personalised to the individual patient can significantly improve outcomes across a range of medical conditions. The closed-loop control approach involves continuously monitoring key clinical parameters and, informed by mathematical models, adapting treatment. The advent of massive computer power, highly sensitive, specific and flexible sensors, and finely-titratable treatments has finally allowed closed-loop control systems to offer a revolutionary leap in medical treatment. Examples of challenges that might now be met include: the delivery of treatment to cancer patients, the moment-to-moment management of critically ill (or injured) patients, and the accelerated healing of chronic wounds. We propose the formation of a multidisciplinary team comprising academics, clinicians and industrialists, supported by stakeholders, to address these challenges.

The first year of the network involves bringing together the community in a series of Grand Challenge Workshops to establish a roadmap. Areas where there are gaps in technology or knowledge will be addressed by eight feasibility studies or secondments that will run during years 2 and 3 and will provide proof of concept data for grand challenge funding applications. These larger funding applications will be developed in parallel to the feasibility studies.
Key Findings
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Further Information:  
Organisation Website: http://www.nottingham.ac.uk