EPSRC Reference: |
GR/T17960/01 |
Title: |
Biomaterials From Sugars: Catalytic Synthesis Of Biodegradable And Functionalised Polymers |
Principal Investigator: |
Williams, Professor CK |
Other Investigators: |
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Researcher Co-Investigators: |
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Project Partners: |
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Department: |
Chemistry |
Organisation: |
Imperial College London |
Scheme: |
First Grant Scheme Pre-FEC |
Starts: |
01 October 2004 |
Ends: |
30 September 2007 |
Value (£): |
119,745
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EPSRC Research Topic Classifications: |
Catalysis & Applied Catalysis |
Chemical Synthetic Methodology |
Drug Formulation & Delivery |
Materials Synthesis & Growth |
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EPSRC Industrial Sector Classifications: |
Chemicals |
Environment |
Pharmaceuticals and Biotechnology |
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Related Grants: |
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Panel History: |
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Summary on Grant Application Form |
Our research involves using renewable resources, and specifically derivatives of glucose, to make polymers which can degrade both in the environment and in the body to give naturally occurring and processible chemicals. These new polymers are not only important as sustainable plastics but are also specifically targeted for applications in Medicine, for example in drug delivery, tissue regeneration and as anti-microbial surfaces. The sugar starting materials are important as renewable resources but are also chosen because they have a plethora of reactive sites from which to change the polymers' chemistry and materials properties according to their application. for example we will be researching how to control water solubility and attachment of other chemicals, such as drugs or metals, to them. A key feature of the research is the metal catalysed synthesis of the polymers, which will be developed by making new catalysts from cheaper, readily available and biocompatible metals. We W11 also aim to elucidate the relationship between the chemical structure of the catalyst and the efficiency and structure of the product polymers. Finally, the new catalysts will enable the synthesis of block copolymers or nanomaterials; species that self-assemble into highly ordered structures on the micro- or nanometre scale. The new polymers will form the basis of future and current collaborations with Medicinal and Physical Chemists both In academe and industry.
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Key Findings |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
Summary |
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Date Materialised |
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Sectors submitted by the Researcher |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Project URL: |
http://www.ch.ic.ac.uk/williams/index.html |
Further Information: |
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Organisation Website: |
http://www.imperial.ac.uk |