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Details of Grant 

EPSRC Reference: GR/S87065/01
Title: Organic synthesis without solvents or reagents.
Principal Investigator: McNab, Professor H
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Sch of Chemistry
Organisation: University of Edinburgh
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 2004 Ends: 30 September 2007 Value (£): 185,829
EPSRC Research Topic Classifications:
Catalysis & Applied Catalysis Chemical Synthetic Methodology
EPSRC Industrial Sector Classifications:
Chemicals Pharmaceuticals and Biotechnology
Related Grants:
Panel History:  
Summary on Grant Application Form
Describe the proposed research using (about 200) words geared to the non-specialist reader. Organic synthesis without solvents or reagents.Many processes in the organic chemical industry are wasteful of materials and energy because of the needless use of solvents. In addition, many processes require reagents which may be toxic, corrosive, expensive and require complex separation methods at the end of the reaction. By proposing to carry out the chemistry at low pressures in the gas-phase, this project aims to eliminate the need for solvents for certain key reactions and by utilising solid catalysts which can be recycled, the need for reagents in many processes will be eliminated. The choice of reactions and catalysts is critical for the sucess of the project and includes dehydration, dehydrogenation and cyclisation methods leading to alkenes, alkynes, carbonyl compounds, aromatics and heteroaromatics. Possible catalysts include silicas, aluminas, zeolites, transition metal oxides and noble metals. Finally, as a direct consequence of these objectives being met, the
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Summary
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Organisation Website: http://www.ed.ac.uk