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EPSRC Reference: GR/S80950/01
Title: UHF probes for functional MRI: optimisation of performance for human brain imaging at 300 MHz
Principal Investigator: Glover, Dr PM
Other Investigators:
Christopoulos, Professor C Benson, Professor TM Bowtell, Professor R
Thomas, Professor D Sewell, Professor PD Vukovic, Dr A
Researcher Co-Investigators:
Project Partners:
Philips Queensland University of Technology
Department: Sch of Physics & Astronomy
Organisation: University of Nottingham
Scheme: Standard Research (Pre-FEC)
Starts: 01 March 2004 Ends: 30 June 2007 Value (£): 237,635
EPSRC Research Topic Classifications:
Image & Vision Computing Med.Instrument.Device& Equip.
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
Magnetic Resonance Imaging systems directed towards advancing our understanding of brain function are now being developed at operating static magnetic field strengths of 7 Tesla and above, corresponding to a proton resonant frequency of over 300 MHz. At these high frequencies, a number of hitherto ignored effects dominate the performance of the transmitter and receiver probes. These include: dielectric effects (losses and tuning stability), wavelength effects (phase retardation) and radiative losses. In general these effects lead to RF inhomogeneities within the head and therefore poor imaging performance. This research aims to develop an understanding of these problems which will inform the design of a range of probes to compensate for these effects. Numerical (Transmission Line Modelling) and analytic techniques will be employed to model the head-probe interactions for a range of probe types including TEM probes, surface coils and multi-coil arrays. Novel designs which exploit the short wavelength will also be explored. A range of optimised probes (some specifically designed for the SENSE technique) will be developed and tested with the goal of delivering the signal-to-noise ratio performance necessary for single shot functional imaging paradigms.
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Organisation Website: http://www.nottingham.ac.uk