| EPSRC Reference: |
GR/S69559/01 |
| Title: |
Basic Technology: Advanced Techniques for Food Characterisation - A Generic Strategy for Application Optimised Detectors |
| Principal Investigator: |
Livingstone, Dr C |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Health and Medical Sciences |
| Organisation: |
University of Surrey |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
21 June 2004 |
Ends: |
20 June 2005 |
Value (£): |
92,196
|
| EPSRC Research Topic Classifications: |
|
| EPSRC Industrial Sector Classifications: |
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
The project will assess the efficacy of using novel, multi-layer array, laminate assemblies as the foundation for the development of a range of electrochemical detectors for use in liquid chromatographic analysis. Procedures required for the fabrication of the assemblies will be developed and the electrode responses and physical properties characterised. Three operating modes - single potential, bipotential redox cycling and coulometric detection would be investigated and their respective properties compared, contrasted and evaluated relative to conventional electrochemical and spectroscopic detection systems. A novel approach to the preparation of multi-channel detectors will be investigated in which the effectiveness of exploiting the variations in analyte reactivity within a multi-substrate array (in contrast to the more conventional multi-potential arrangements) would be assessed. The target application would involve the utilisation of the detectors for the ion-exchange chromatographic (HPAEC) characterisation of dietary supplements and their subsequent influence on physiological levels of key biomarkers. Validation of the various approaches would be routinely assessed throughout the lifetime of the project and generic methods for analysing the amino acid, aminothiol, carbohydrate and organic acid composition of both the dietary supplements and clinical samples will be developed and be subject to inter-laboratory checks.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
http://www.surrey.ac.uk |