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Details of Grant 

EPSRC Reference: GR/S34083/02
Title: Facility access for fellowship on high-resolution impedance imaging for materials characterisation and life science applications
Principal Investigator: Krause, Dr S
Other Investigators:
Researcher Co-Investigators:
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Department: Materials
Organisation: Queen Mary University of London
Scheme: Standard Research (Pre-FEC)
Starts: 01 March 2004 Ends: 31 October 2008 Value (£): 44,823
EPSRC Research Topic Classifications:
Biomaterials Materials Characterisation
Surfaces & Interfaces
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
This proposal is aimed at gaining access to the microelectronics facility in Southampton and the III/V semiconductor facility in Sheffield to carry out the work I proposed to do during my recently awarded EPSRC advanced fellowship (GR/R76035). No other funding is requested. The work described in this proposal has already gone through the peer review process (see GR/R76035).A new imaging technique - Scanning Photo-induced Impedance Microscopy (SPIM) has been developed. It is capable of measuring the local impedance of thin films with good lateral resolution. Investigations of model systems have shown very promising results. In this programme, the resolution and the sensitivity of the new technique will be pushed to their limits in order to develop it into an attractive tool for the characterisation of the local properties of materials and biological systems. The main focus of this research will be on the optimisation of the semiconductor substrates required for SPIM and the improvement of the optical setup. Potential applications of the imaging technique have been identified covering a wide range of different subject areas such as medicine, materials characterisation, membrane proteins and biosensors. Among others, biosensor arrays capable of detecting proteases released at sites of inflammation and infection will be developed.
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