Details of Grant

EPSRC Reference:

GR/S23483/01

Title:

Basic Technology: Optical Biochips

Principal Investigator:

Other Investigators:

Smowton, Professor PM	Ameer-Beg, Professor SM	Westwood, Dr D
Blood, Professor P	Burt, Dr J	Vojnovic, Professor B
Summers, Professor H	Errington, Dr RJ	Taylor, Professor DM

Researcher Co-Investigators:

Project Partners:

IQE PLC	Kings College London	Oxford Optronix Ltd
University of Strathclyde

Department:

Division of Clinical Laboratory Science

Organisation:

Cardiff University

Scheme:

Standard Research (Pre-FEC)

Starts:

01 July 2003

Ends:

31 December 2007

Value (£):

2,271,606

EPSRC Research Topic Classifications:

Bioelectronic Devices

Optical Devices & Subsystems

EPSRC Industrial Sector Classifications:

Pharmaceuticals and Biotechnology

No relevance to Underpinning Sectors

Related Grants:

Panel History:

Summary on Grant Application Form

The demand for biological analyses is undergoing explosive growth. Moving analyses to the micro level offers important economies scale but also opens up exciting opportunities. The project aims to bring down to a micro-scale all of the main components of the lig emitting and collecting devices used to analyse biological samples in a modern life sciences laboratory including lasers the size of a single human cell. This optical laboratory on a chip will be integrated with specially engineered micro trafficking systems that can me samples and live cells around for processing. These optical biochips , will use light to excite specially designed fluorescent chemical that can reveal important features about each cell such as how it responds to a drug or whether or not it is diseased. In creating these portable credit-card sized devices basic technological problems will be solved with massive benefits both to research from physics to medicine and to UK competitiveness. This basic technological know-how would bring widespread practical benefits such as increasit the success rate of drug discovery, in genomics research, in the routine diagnosis of disease, developing new ways for the rapid transmission of information and operation of ultra-fast computers.

Key Findings

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Potential use in non-academic contexts

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Impacts

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Summary
Date Materialised

Sectors submitted by the Researcher

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Project URL:

Further Information:

Organisation Website:

http://www.cf.ac.uk