| EPSRC Reference: |
GR/S23315/01 |
| Title: |
Charge Separation Mechanisms in Donor-Acceptor Systems using Nucleic Acids as Rigid Scaffolds |
| Principal Investigator: |
Tuite, Dr EM |
| Other Investigators: |
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| Project Partners: |
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| Department: |
School of Chemistry |
| Organisation: |
Newcastle University |
| Scheme: |
First Grant Scheme Pre-FEC |
| Starts: |
06 February 2004 |
Ends: |
05 February 2007 |
Value (£): |
119,752
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| EPSRC Research Topic Classifications: |
| Biological & Medicinal Chem. |
Chemical Biology |
| Materials Characterisation |
Surfaces & Interfaces |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Electronics |
| Healthcare |
Pharmaceuticals and Biotechnology |
| No relevance to Underpinning Sectors |
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| Panel History: |
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Summary on Grant Application Form |
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The question of whether DNA can conduct electrons remains controversial although recent studies are providing increasing insight. We approach the problem from several angles. Firstly, can DNA mediate electron mobility between donor and acceptor molecules that cannot access the bridge states of the bases; secondly, if donors and acceptors can oxidise the bases either completely or transiently, how far and how fast can electrons travel along DNA; thirdly, can we use nucleic acids (including synthetic analogues such as PNA) to assemble multicomponent compartmentalised electron relay systems for long range charge separation? Our goal is to design systems in which nucleic acids can be used as molecular scaffolding to facilitate directional charge separation and storage, or potentially in which base-modified nucleic acids can act as molecular wires.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.ncl.ac.uk |