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Details of Grant 

EPSRC Reference: GR/S15952/01
Title: Lanthanide Spectroscopic Probes: reversible binding to amino acids, peptides and proteins
Principal Investigator: Parker, Professor D
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: Durham, University of
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 2003 Ends: 30 September 2006 Value (£): 93,902
EPSRC Research Topic Classifications:
Biological & Medicinal Chem. Chemical Biology
EPSRC Industrial Sector Classifications:
Pharmaceuticals and Biotechnology No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
A study of the nature and selectivity of the reversible binding interaction between cationic, anionic and neutral enantiopure Ln complexes and the common amino acids using NMR, CD, CPL and luminescence emission spectroscopy. Extension to selected C- and N-terminal peptide models, various tetrapeptides and three proteins of varing pl, the latter study embracing HPLC analysis of relative binding affinity.
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