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Details of Grant 

EPSRC Reference: GR/S12210/01
Title: Development of a practical technique to deliver intensity-modulated radiation therapy (IMRT) with jaws and a mask
Principal Investigator: Webb, Professor S
Other Investigators:
Symonds-Tayler, Mr JRN Evans, Professor P
Researcher Co-Investigators:
Project Partners:
Department: Physics
Organisation: Institute of Cancer Research
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 2003 Ends: 31 March 2007 Value (£): 69,279
EPSRC Research Topic Classifications:
Image & Vision Computing Instrumentation Eng. & Dev.
EPSRC Industrial Sector Classifications:
Related Grants:
Panel History:  
Summary on Grant Application Form
Intensity modulated radiotherapy (IMRT) is presently deliverable using either the commercial multileaf collimator (MLC) or the NOMOS MIMIC. This project will develop an IMRT technique for those Centres with a linac without an MLC and/or for a Co-60 machine (which has no MLC). The concept is already proven (Webb 2002a,b). This studentship will take on the next step of designing a practical system and constructing a prototype. Then the practical issues of incorporating the effects of scatter, attenuator transmission and matching penumbras will be studied. The effects of a finite focal sp size for Co-60 will be studied. The design will take into account the requirement to sequence the masks for each sequential field component in a practical time. This will involve considering several competing techniques to create the mask shapes and also the design of computer sequencing techniques including simulated annealing to solve the sequencing problem. Once constructed and with the problems of considering non-primary radiation solved, the prototype collimator will be used to deliver some practical IMRT fields from a commercial treatment-planning system.
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