| EPSRC Reference: |
GR/R94800/01 |
| Title: |
FUNDAMENTAL STUDIES OF PARTICLE GENERATION BY FREEZE DRYING |
| Principal Investigator: |
Wilson, Professor DI |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Chemical Engineering and Biotechnology |
| Organisation: |
University of Cambridge |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 July 2002 |
Ends: |
31 July 2003 |
Value (£): |
78,841
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| EPSRC Research Topic Classifications: |
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| EPSRC Industrial Sector Classifications: |
| Manufacturing |
Food and Drink |
| Pharmaceuticals and Biotechnology |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Spray drying is an established technology for the generation of particulates from solutions or suspensions, but it conventionally features a hot gas phase, which is not suitable for certain components or products. Spray freeze crystallisation can yield a fine dispersion of frozen powder with complex microstructures, which can be used to seed subsequent products, or dried to give porous particulates. This project will employ magnetic resonance (MR) imaging techniques, developed at the Magnetic Resonance Research (MRRC) at Cambridge, to investigate fundamental aspects of the spray freezing technology, building on recent work at the Department of Chemical and Materials Engineering at the University of Auckland (NZ). Spray freezing lends itself readily to MR investigations, as the solid and liquid phases can be readily identified by modern fast imaging techniques; other MR techniques will be used to probe the composition and microstructure of the products generated. The results obtained using aqueous solutions will be compared with those optained using video techniques at Auckland, while those obtained for opaque systems will be unique. The proposal seeks funding for the main investigator at Auckland, Jason Hindmarsh, to spend 12 months at the MRRC in Cambridge as a post-doctoral researcher. The spray freezing apparatus will be constructed in Auckland and brought to the UK by Mr. Hindmarsh.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.cam.ac.uk |