| EPSRC Reference: |
GR/R92004/01 |
| Title: |
Dissolving Biomolecules in Supercritical Fluids: Fundamentals and Applications |
| Principal Investigator: |
Poliakoff, Professor M |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Nottingham |
| Scheme: |
ROPA |
| Starts: |
01 October 2002 |
Ends: |
31 March 2005 |
Value (£): |
115,809
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| EPSRC Research Topic Classifications: |
| Catalysis & Applied Catalysis |
Gas & Solution Phase Reactions |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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This Proposalinvolves a completely new approach to dissolving biomolecules in supercritical CO2 (scCO2) using hydrophobic ion pairing (HIP) by CO2-philic surphactants. Preliminary results are very encouraging. Our objectives are: (i) to demonstrate in situ catalytic activity of enzymes while dissolved in scCO2 (ii) to identify a range of less expensive HIP surfactants for use in CO2 and other supercritical fluids (iii) to establish whether the HIPapproach can be extended to DNA. We believe that the project is adventurous; it combines wide academic interest with significant industrial benefits, ranging from fine chemicals manufacture to environmentally more benign dry-cleaning. Our application is backed by unrelated industrial funding.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.nottingham.ac.uk |