| EPSRC Reference: |
GR/R90437/01 |
| Title: |
Faraday Fast Track: Novel biocompatible diblock copolymers as gene delivery vehicle |
| Principal Investigator: |
Lu, Professor J |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Physics and Astronomy |
| Organisation: |
University of Manchester, The |
| Scheme: |
Faraday (PreFEC) |
| Starts: |
01 August 2003 |
Ends: |
31 July 2006 |
Value (£): |
114,775
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| EPSRC Research Topic Classifications: |
| Biological & Medicinal Chem. |
Complex fluids & soft solids |
| Drug Formulation & Delivery |
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| EPSRC Industrial Sector Classifications: |
| Pharmaceuticals and Biotechnology |
No relevance to Underpinning Sectors |
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| Panel History: |
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Summary on Grant Application Form |
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Diblock DMA-MPC copolymers are designed with careful consideration of minimal toxicity. Their molecular architectures are expected to lead to novel interfacial and bulk micellar aggregation that provides ideal molecular environment for DNA incorporation. We aim to explore the suitable molecular architecture that intelligently responds to solution conditions for DNA delivery. The project involves the combined investigation of the interfacial and bulk aggregation behaviour of the copolymers and their cytotoxicity to model cells.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.man.ac.uk |