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Details of Grant 

EPSRC Reference: GR/R69624/01
Title: Telescoped Organic Processes using Potentially Self-destructive Reagents
Principal Investigator: Taylor, Professor R
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: University of York
Scheme: ROPA
Starts: 01 November 2002 Ends: 31 May 2005 Value (£): 85,451
EPSRC Research Topic Classifications:
Chemical Synthetic Methodology
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors Chemicals
Related Grants:
Panel History:  
Summary on Grant Application Form
The aim of this proposal is to develop Telescoped Organic Processes using Potentially Self-destructive Reagents (TOPUPS).TOPUPS procedures enable two, three or more conventional reactions to be carried out in a single process leading to a reduction in the number of operations (e.g. isolation and purification) and thus to a major cost benefit. In addition, such a sequence may enable difficult intermediates to be accessed, and elaborated in situ, without the need for isolation.The initial aim of this proposal is to develop and apply one-pot, TOPUPS methods leading directly from alcohols to imines, amines and heterocycles.
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Summary
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Organisation Website: http://www.york.ac.uk