| EPSRC Reference: |
GR/R67620/01 |
| Title: |
Chiral 'PCP'-and 'PNP'-Pincer Ligands For Asymmetric Catalysis |
| Principal Investigator: |
Bedford, Professor RB |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
University of Exeter |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
15 March 2002 |
Ends: |
14 March 2005 |
Value (£): |
199,227
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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We will synthesise a range of new, chiral bis(phosphine), bis(phosphite), bis(phosphonite) and bis(phosphinite) 'PCP- and 'PNP'-pincer ligands. Late transition metal complexes of these ligands will be tested as catalysts in asymmetric Heck, Suzuki, cyclopropanation, Lewis acid catalysed, aldol and transfer hydrogenation reactions. This study will inform us as to which ligands and catalysts to optimise in these reactions for best activity and stereoselectivity. It is anticipiated that many of the comple)s will show high stereoselectivity as a result of the 'deep chiral pock' formed by the pincer ligands on the metal's coordination sphere.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.ex.ac.uk |