| EPSRC Reference: |
GR/R60195/01 |
| Title: |
New methods for Hydrazone Oxidation and Applications to a catalytic process for Olefin Synthesis |
| Principal Investigator: |
Aggarwal, Professor VK |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
University of Bristol |
| Scheme: |
ROPA |
| Starts: |
29 April 2002 |
Ends: |
28 April 2004 |
Value (£): |
100,370
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| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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Diazocompounds are useful intermediates but are underused due to the hazards associated with handling these potentially explosive reagents. Our aim is to develop an environmentally friendly oxidation of hydrazones into diazocompounds using suitably mild conditions so that the diazocompound can then be reacted in situ. We will then couple the hydrazone oxidation to our existing epoxidation technology. We also aim to develop a non-Wittig-mediated synthesis of alkenes using metathasis. We will attempt to find conditions under which, following metal mediated hydrazone oxidation, the metal further takes part in diazodecomposition to give a metallocarbene which then reacts with an aldehyde to give an alkene and returns the high oxidation state metal for further catalysis. In this redox process, no oxidant is required and alkenes would be synthesised from hydrazones and aldehydes with only water and nitrogen as by-products.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bris.ac.uk |