| EPSRC Reference: |
GR/R44409/01 |
| Title: |
Surface Analysis of Orthopaedic Implants |
| Principal Investigator: |
Allen, Professor GC |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Interface Analysis Centre |
| Organisation: |
University of Bristol |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 February 2002 |
Ends: |
31 January 2005 |
Value (£): |
208,258
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Summary on Grant Application Form |
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This collaborative proposal between the Interface Analysis Centre at the University of Bristol and Southmead Hospital, Bristol, aims to apply recently developed state-of-the-art surface analytical techniques to the study of the degradation of commonly used metal prosthetic implants. By using a range of surface analytical techniques including high resolution secondary ion mass spectrometry (SIMS), inductively-coupled plasma mass spectroscopy (ICPMS), laser and Fourier Transform (FT) Raman spectroscopy, X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM), we propose to characterise the behaviour of prosthetic implants such as hip replacement joints by analysing their surfaces, the particles which they shed and the tissue which surrounds them. We intend to establish a link between genetic damage which occurs to cells surrounding the wear debris and the surface chemistry of the wear particles. The surface chemistry of the implants and the shed particles is of paramount importance in determining their behaviour in the body and therefore their long-term performance.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bris.ac.uk |