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Details of Grant 

EPSRC Reference: GR/R40654/01
Title: Computerised Analysis of Expiratory Airflow Profiles as a Diagnostic Tool for Detecting Airway Obstruction
Principal Investigator: Williams, Professor EM
Other Investigators:
Jones, Professor B Davies, Professor B
Researcher Co-Investigators:
Project Partners:
Department: Sch of Applied Sciences
Organisation: University of Glamorgan
Scheme: Fast Stream
Starts: 01 September 2001 Ends: 31 August 2003 Value (£): 62,272
EPSRC Research Topic Classifications:
Digital Signal Processing Intelligent & Expert Systems
Med.Instrument.Device& Equip.
EPSRC Industrial Sector Classifications:
Healthcare Information Technologies
Related Grants:
Panel History:  
Summary on Grant Application Form
The diagnosis of lung airway obstruction using expiratory airflow patterns has advanced significantly in the last 5 years. These advances have been made possible by applying simple computerised data analysis and pattern recognition techniques. The indices of airway obstruction that have been derived are successful in diagnosing most cases of severe airflow obstruction. However in some disee states where the obstructive airway disee is less severe, then the sensitivity of these indices is decreed. One aim of this study is to develop more efficient signal processing algorithms, to extract the expiratory flow data from the inspiratory flow data. The second and more important aim is use sophisticated techniques to analyse the expiratory flow profiles so that the subtle changes in profile can be objectively meured and quantitatively characterised. In other are of biological science similar signal analysis procedures have changed the understanding of the regulatory mechanisms and have led to more sophisticated analysis regimes (Eg ECG analysis). The same should be true for signals derived from the respiratory system. The collection of tidal airflow, patterns is simple and although more variable than the ECG should still contain a wealth of data that can used to improve the diagnosis of obstructive airway disee.
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Organisation Website: http://www.glam.ac.uk