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Details of Grant 

EPSRC Reference: GR/R27846/01
Title: Microwave Coagulation Therapy For Liver Cancer
Principal Investigator: Alford, Professor N
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Engineering Systems
Organisation: London South Bank University
Scheme: Standard Research (Pre-FEC)
Starts: 01 June 2002 Ends: 31 August 2004 Value (£): 112,078
EPSRC Research Topic Classifications:
Instrumentation Eng. & Dev.
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
GR/R27853/01
Panel History:  
Summary on Grant Application Form
The programme will seek to develop a new range of microwave applicators for the treatment of liver cancer. These applicators will use high permittivity dielectric materials to a) match the microwave power to tissue and b) encapsulate the new field of the primary radiating element within low loss material. We believe that by doing this we will substantially increase the diameter of the heated region compared to other applicator designs. We will also develop a TWT based microwave system working in the range 2 to 8 G Hz which will be computer controlled and agile in both frequency and power. By controlling these parameters and using the changes in dielectric properties that occur during a treatment we can produce a controlled coagulation region matched to the size of a particular tumour. We envisage two modes of treatment a) MCT in association with open surgery and surgical excision of the majority of tumour material b) minimally invasive - either laparoscopic or percutaneous. Our goal will be to develop and test applicators suitable for both of these modalities.
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Organisation Website: http://www.lsbu.ac.uk