| EPSRC Reference: |
GR/R16365/01 |
| Title: |
(Ropa) Template-Modified Sulphur-Tolerant Catalysts For Hydrogenation of Sulphur-Containing Drug Precursors |
| Principal Investigator: |
Burch, Professor R |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Sch of Chemistry and Chemical Eng |
| Organisation: |
Queen's University of Belfast |
| Scheme: |
ROPA |
| Starts: |
02 July 2001 |
Ends: |
01 September 2003 |
Value (£): |
106,164
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| EPSRC Research Topic Classifications: |
| Catalysis & Applied Catalysis |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
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| Related Grants: |
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| Panel History: |
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Summary on Grant Application Form |
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Recent drugs research, based on compounds such as Cefadroxil has resulted in the synthesis of compounds with the grouping R-C=C-S-R in which the S atom and the ' C=C bond are in close proximity. However, there is a problem with the hydrogenation of these C=C bonds under the mild conditions used in the pharmaceutical industry because conventional metal catalysts are poisoned by the organo-sulphur compound. The aim of this research is to overcome this problem by developing the concept of surface templating in order to control the access of the organo-sulphur compound to the active metal surface.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.qub.ac.uk |