| EPSRC Reference: |
GR/R14545/01 |
| Title: |
Uniformly-Sized Molecularly Imprinted Polymer Particulates Tailored For Applications In Chemical Analysis |
| Principal Investigator: |
Cormack, Professor P |
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| Project Partners: |
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| Department: |
Pure and Applied Chemistry |
| Organisation: |
University of Strathclyde |
| Scheme: |
Fast Stream |
| Starts: |
19 March 2001 |
Ends: |
18 September 2002 |
Value (£): |
62,591
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| EPSRC Research Topic Classifications: |
| Analytical Science |
Materials Synthesis & Growth |
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Summary on Grant Application Form |
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This project aims to establish precipitation polymerisation as an attractive, general method for the rapid production of molecularly imprinted polymers in a highly desirable spherical, particulate form. Sub-micron-sized imprinted polymer microspheres prepared via precipitation polymerisation have already demonstrated their considerable potential in radio-Iigand binding assays and capillary electrochromtography and shown clear advantages over polymers prepared via conventional methods. However further developments in the methodology are essential to enable such materials to be routinely applied in solid-phase extraction and high performance liquid chromatograph This project aims to satisfy this demand. A further goal of the proposed research described herein is to use precipitation polymerisation as a convenient polymerisation method for the preparation of imprinted polymers with core-shell morphologies It is anticipated that several of the disadvantages associated with state-of-the-art imprinted polymers can be addressed by using polymerswith such morphologies, e.g. poor mass-transfer kinetics and template bleeding. Finally the development of particles with core-shell morphologies where the imprinted shell is supported will enable polymer compositions outwith those normally exploited in imprinting to be investigated It is expected that such an approach will help to address the template bleeding issue which is holding back those wishing to apply imprints in ultra-trace analysis as well as the other well-documented limitations associated with state-of-the-art imprinted materials.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.strath.ac.uk |