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Details of Grant 

EPSRC Reference: GR/R03204/01
Title: IMI: Activated Carbon Haemoadsorbents For the Removal of Middle Molecular Weight and Other Toxins From Blood
Principal Investigator: Hellgardt, Professor K
Other Investigators:
Hoenich, Dr N Warwick, Dr G
Researcher Co-Investigators:
Project Partners:
Brighton Health Care NHS Trust Craig Medical Products Ltd Guy's and St Thomas Hospital Trust
Mast Carbon Ltd Purolite
Department: Chemical Engineering
Organisation: Loughborough University
Scheme: LINK
Starts: 01 October 2000 Ends: 30 September 2003 Value (£): 248,179
EPSRC Research Topic Classifications:
Medical science & disease Separation Processes
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
GR/R05154/01
Panel History:  
Summary on Grant Application Form
The research programme comprises: (1) The design and manufacture of novel heamoadsorbents based on uncoated polymer pyrolised activated carbons. (2) The development of prototype extracorporeal devices for removal of uraemic toxins from the circulation of patients with renal and multi-organ failure. (3) Medical grade activated carbons will be evaluated during in vitro studies to demonstrate the effective removal of low and middle molecular weight uraemic toxins from blood. (4) Haemo/biocompatibility of the adsorbents in order to prevent the formation of microemboli will be investigated. (5) Regeneration of spent adsorption columns will be studied to evaluate the potential for repetitive use. (6) A preliminary cost-benefit analysis will be performed of the extracorporeal adsorption technique for the treatment of patients with acute and chronic renal failure.
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Further Information:  
Organisation Website: http://www.lboro.ac.uk