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Details of Grant 

EPSRC Reference: GR/N35489/01
Title: NEW MASS SPECTROMETER FOR SYNTHETIC CHEMISTRY AT THE UNIVERSITY OF EXETER
Principal Investigator: Shipman, Professor M
Other Investigators:
Moody, Professor CJ Bruce, Professor D Tucker, Professor JH
Coldham, Professor I
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: University of Exeter
Scheme: Standard Research (Pre-FEC)
Starts: 01 December 2000 Ends: 30 November 2003 Value (£): 257,406
EPSRC Research Topic Classifications:
Biological & Medicinal Chem. Catalysis & Applied Catalysis
Chemical Synthetic Methodology Co-ordination Chemistry
EPSRC Industrial Sector Classifications:
Chemicals Pharmaceuticals and Biotechnology
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
Synthetic chemistry is a major activity within the School of Chemistry, a discipline which is highly dependent upon ready access to a range of spectroscopic facilities for compound characterisation. This proposal deals with urgent upgrading of our mass spectrometry facilities especially in regard to the acquisition of accurate mass measurements on molecular ions and fragments. As such measurements are essential during the characterisation of new compounds produced by chemical synthesis, it is anticipated that the provision of this new instrument will greatly enhance a variety of existing and future organic, inorganic and materials programmes.Specific research programmes that will benefit include:(i) Total synthesis of complex natural products (amythiamycin A, azinomycins, ficellomycin, manzamines).(ii) New synthetic methods (methyleneaziridines, chiral oxime ethers, chiral dirhodium catalysts, anionic cyclisations).(iii) Materials and Coordination Chemistry (Metallomesogens, Biaxial Nematic Liquid Crystals).(iv) Supramolecular Chemistry and Sensing (receptors for neutral molecules, DNA bases and amino acids; photochemical molecular logic gates).
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Summary
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Further Information:  
Organisation Website: http://www.ex.ac.uk