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Details of Grant 

EPSRC Reference: GR/N16778/01
Title: ANATOMICAL MODELS FOR CALIBRATION OF BLOOD VELOCITY MEASUREMENTS MADE USING DOPPLER ULTRASOUND
Principal Investigator: Black, Dr RA
Other Investigators:
Sutcliffe, Professor CJ O'Neill, Professor W
Researcher Co-Investigators:
Project Partners:
Collected Consultants Ltd Materialise Ltd
Department: Clinical Engineering
Organisation: University of Liverpool
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 2000 Ends: 31 December 2003 Value (£): 133,478
EPSRC Research Topic Classifications:
Development (Biosciences) Instrumentation Eng. & Dev.
Intelligent Measurement Sys. Multiphase Flow
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors Healthcare
Related Grants:
GR/N16747/01
Panel History:  
Summary on Grant Application Form
Improved diagnosis of arterial disease relies on the development of non-invasive methods to measure blood velocity and related quantities (eg wall shear rate and volumetric flow) and these methods must be accurate in the complex 3D flows occurring in-vivo. Accuracy cannot be assessed in-vivo, and the flow field in straight tube models is not representative of that in real vessels. This project develops anatomical flow models with known velocity fields suitable for assessment of velocity accuracy measured using Doppler ultrasound. An acoustically equivalent polyurethane suitable for making the vessel wall will be developed. Mould manufacture will use rapid prototyping techniques based on 3D MRI datasets from human arteries. The vessel wall movement of the models is measured optically and adjusted to match that of human arteries. Acoustically equivalent models and identical optically transparent models are built. Knowledge concerning the 3D time varying flow field is obtained using the optical models; velocity is measured using an optical tracking technique. The models are used to investigate the accuracy of maximum velocity and volumetric flow measured using commercial Doppler systems, maximum velocity measured using a prototype real time dual beam Doppler system, and wall shear rate measured using a prototype colour flow technique.EngProg\
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Summary
Date Materialised
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Further Information:  
Organisation Website: http://www.liv.ac.uk