| EPSRC Reference: |
GR/N07462/01 |
| Title: |
FROM CRYSTALS TO CURES: PROBLEMS WITH SOLID-STATE PHARMACEUTICALS |
| Principal Investigator: |
Florence, Professor AJ |
| Other Investigators: |
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| Researcher Co-Investigators: |
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| Project Partners: |
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| Department: |
Inst of Pharmacy and Biomedical Sci |
| Organisation: |
University of Strathclyde |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
18 July 2000 |
Ends: |
17 July 2003 |
Value (£): |
60,000
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| EPSRC Research Topic Classifications: |
| Biological & Medicinal Chem. |
Chemical Structure |
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| EPSRC Industrial Sector Classifications: |
| Pharmaceuticals and Biotechnology |
No relevance to Underpinning Sectors |
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| Panel History: |
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Summary on Grant Application Form |
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This application seeks funding for an X-ray powder diffractometer. XRPD will allow routine characterisation and identification of polycrystalline powders to be carried out but primarily will enable two principal research projects:Project A: Crystallisation and polymorphism in oligosaccharide ester derivatives; specifically, correlating the structural and physical properties of these compounds in the context of their use in controlled-delivery of pharmaceutical active agents.Project B: Crystal structures from laboratory XRPD data; NOT the development of software tools for crystal structure solution, but the application of proven structure-solving methods to problems where single crystals cannot be obtained. Specific targets include zopiclone and norfloxacin, and objectives include the development of guidelines on optimising data collection and processing, with a view to maximising the chances of structure solution.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.strath.ac.uk |