| EPSRC Reference: |
GR/M99477/01 |
| Title: |
ANION-DIRECTED SELF ASSEMBLY OF SUPRAMOLECULAR CAGES |
| Principal Investigator: |
Ward, Professor MD |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Chemistry |
| Organisation: |
University of Bristol |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 October 2000 |
Ends: |
30 September 2003 |
Value (£): |
184,567
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| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| Chemicals |
No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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We have shown in recent preliminary studies that tetrahedral cage complexes, based on labile transition-metal ions and multidentate bridging ligands, can assemble around a templating anion which remains trapped in the cavity of the cage. The proposed project is to exploit systematically this novel self-assembly method by preparing a variety of suitable bridging ligands, and investigating their reactions with labile metal ions in the presence of a variety of possible anions of different shapes, sizes and charges which can act as templates. A combination of solid-state (X-ray crystallography) and solution (nultinuclear NMR, electrospray mass spectrometry) studies will be used to investigate the ability of different anions to control assembly of the cationic cages around them; the kinetics of the assembly processes; and the ability of the cages to trap different guests in competition experiments. We will also examine the consequence of the high inherent chirality of these cage complexes: viz. (i) can an optically pure anion control the chirality of the cage which assembles around it, and (ii) can an optically pure cage complex preferentially recognise one enantiomer of a chiral anion.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bris.ac.uk |