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Details of Grant 

EPSRC Reference: GR/M92546/01
Title: (JREI) A CRYOPROBE FOR HIGH SENSITIVITY NMR
Principal Investigator: Ley, Professor S
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Bruker
Department: Chemistry
Organisation: University of Cambridge
Scheme: JREI
Starts: 01 March 2000 Ends: 28 February 2003 Value (£): 95,566
EPSRC Research Topic Classifications:
Catalysis & Applied Catalysis Chemical Synthetic Methodology
EPSRC Industrial Sector Classifications:
Chemicals Pharmaceuticals and Biotechnology
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
The equipment would underpin the research of over 350 postgraduate and postdoctoral workers requiring advanced NMR spectroscopic facilities in the department of Chemistry. The requested CryoProbe would support a wide range of research programmes. These include:- Development of methodology for the synthesis of biologically active natural products and complex oligosacharides.- Molecular recognition and catalysis in solution, solids and at interfaces.- The chemistry and enzymology of polyketide synthases.- The development of practical methods for stereochemical control.- Natural products and functional macromolecules.- Aminoglycoside and glycopeptide antibiotics.- The mechanism of action of glycopeptide antibiotics.- Combinatorial Chemistry.- Development of stereo- and regio-selective catalysts confined within mesoporous silica and of the organometallic chemistry of cluster supported arene and arene-like compounds.- Silicon-based Control of Organic Reactions.- Methods for stereoselective synthesis using sulfur compounds.
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Further Information:  
Organisation Website: http://www.cam.ac.uk