EPSRC logo

Details of Grant 

EPSRC Reference: GR/M91433/01
Title: (JREI) STRUCTURAL CHEMISTRY WITH CCD DIFFRACTOMETER
Principal Investigator: Muir, Dr K
Other Investigators:
Mallinson, Dr P Spicer, Dr MD Kennedy, Dr AR
Farrugia, Dr L J Mulvey, Professor R Kocienski, Professor P
Researcher Co-Investigators:
Project Partners:
Enraf-Nonius Ltd
Department: School of Chemistry
Organisation: University of Glasgow
Scheme: JREI
Starts: 01 July 2000 Ends: 30 June 2003 Value (£): 124,065
EPSRC Research Topic Classifications:
Chemical Structure
EPSRC Industrial Sector Classifications:
Manufacturing Chemicals
Electronics Pharmaceuticals and Biotechnology
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
Glasgow (GU) and Strathclyde (SU) Universities, in collaboration with Nonius UK, intend to set up a jointly operated Chemical Crystallography Laboratory which will establish optimum data collection and processing procedures for charge density studies with the new Kappa CCD diffractometer. The new laboratory will also provide GU and SU chemists with local access to a modern CCD diffractometer. This will have a major impact of key research programmes in both institutions and will benefit more than twenty separate projects. Many of these projects involve active collaboration with industrial partners, including AgrEvo, Associated Octel Co. Ltd., BP Chemicals, CIBA Speciality Chemicals, Glaxo-Wellcome, Johnson-Matthey, Merck, Pfizer, Rhone-Poulenc-Rorer, Roche, Shell, SmithKline Beecham, and Zeneca. The main areas of activity are:(1) Charge density studies on hydrogen bonded systems and on transition metal organometallics and coordination compounds. This will involve a collaboration with the instrument suppliers Nonius UK.(2) Organo-main group chemistry - novel mixed s-block metal amide molecular oxide species and Li, Mg, & Al-based reagents.(3) Organic synthesis: characterisation of key intermediates in the synthesis of novel compound families important to medicine and agriculture.(4) Design of new materials, including organic hydrates, ionic liquid crystals, and supramolecular assemblies with electron transfer capability.(5) Solid state dynamics of transition metal clusters.(6) Transition metal chemistry - modification of metallic properties via rational ligand design.Single crystal X-ray analysis provides information about the three-dimensional arrangement of atoms in solids which is often essential for chemical characterisation. Furthermore, it is the only technique available for the experimental determination of the molecular electron density distributions which largely define chemical behaviour.The advancment of the CCD diffractometer now allows a single crystal diffraction experiment to be completed in hours rather than days and greatly extends the types of sample wich can be studied. A CCD diffractometer will therefore be used to expand the existing research programmes in structural chemistry at SU and GU and to extend the application of the technique to areas of chemistry which previously avoided its use owing either to its perceived slowness or to lack of access.
Key Findings
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Potential use in non-academic contexts
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Impacts
Description This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Summary
Date Materialised
Sectors submitted by the Researcher
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Project URL:  
Further Information:  
Organisation Website: http://www.gla.ac.uk