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Details of Grant 

EPSRC Reference: GR/M91105/01
Title: NETWORK: SOLUTION PHASE STRUCTURAL CHARACTERIZATION OF LARGE AND COMPLEX MACROMOLECULAR BIOLOGICAL ASSEMBLIE
Principal Investigator: Rodger, Professor A
Other Investigators:
Unwin, Professor P Robinson, Professor C Woolfson, Professor DN
Researcher Co-Investigators:
Project Partners:
Chalmers University of Technology Jasco
Department: Chemistry
Organisation: University of Warwick
Scheme: Standard Research (Pre-FEC)
Starts: 22 November 1999 Ends: 21 August 2003 Value (£): 51,587
EPSRC Research Topic Classifications:
Biological & Medicinal Chem.
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
Large and complex macro-molecular protein and nucleic acid assemblies are increasingly being recognised as the focal point for much of the chemistry in biological systems no molecule acts on its own. As biologists are becoming able to create macromolecular assemblies of direct biological relevance in a controlled and reproducible manner the available standard techniques for characterising them are insufficient either due to artefacts or limited resolution. Thus, progress in a number of exciting biological areas is hindered by absence of appropriate techniques and expertise to develop new methods in biology departments. Only collaborations between biologists and biophysical chemists will enable key biological problems to be solved.The aim of the proposal is to enable collaboration between physical chemists, biophysicists, biologists and an instrumentation engineer all of whom are currently working towards addressing the problem of how structurally to characterise complex molecular assemblies in quite different contexts. The network will build on existing relationships as well as develop new initiatives. It will result in equipment and method development, technology transfer in addition to directly addressing the issue of characterising large and complex biological macromolecular systems.
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Further Information:  
Organisation Website: http://www.warwick.ac.uk