| EPSRC Reference: |
GR/M88990/01 |
| Title: |
AN IMPLANT FOR CONTROLLING NEUROGENIC INCONTINENCE BY COMBINING CONDITIONAL NEUROMODULATION WITH STIMULATION |
| Principal Investigator: |
Donaldson, Professor N. de N. |
| Other Investigators: |
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| Project Partners: |
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| Department: |
Medical Physics and Biomedical Eng |
| Organisation: |
UCL |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
01 November 1999 |
Ends: |
30 April 2003 |
Value (£): |
320,456
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| EPSRC Research Topic Classifications: |
| Biomaterials |
Med.Instrument.Device& Equip. |
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Summary on Grant Application Form |
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We propose to design an implant system which can be used by clinical researchers to investigate new methods for treating neurogenic incontinence. The implant will allow both ENG recording from, and selective stimulation of the afferent and efferent pathways of the sacral nerve roots. Our proposed implant will avoid the need to cut the sensory nerves by using conditional neuromodulation. In addition to being more popular with patients with complete spinal cord lesions, successful use of neuromodulation will widen the user group to include incomplete-lesion patients. The latter will also benefit to the extent that pain can be prevented. All patients may benefit from improved defecation. It is also possible that the device could benefit some patients with other neurological conditions (eg. Multiple Sclerosis).The two major parts of the project are the design of a 4-channel ENG amplifier integrated circuit and the design of the complete implant system. Prototype implants will be produced.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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