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Details of Grant 

EPSRC Reference: GR/M86361/01
Title: INTERMOLECULAR RADICAL REACTIONS
Principal Investigator: Caddick, Professor S
Other Investigators:
Researcher Co-Investigators:
Project Partners:
GlaxoSmithKline plc (GSK)
Department: Chemistry
Organisation: University of Sussex
Scheme: Standard Research (Pre-FEC)
Starts: 01 May 2000 Ends: 31 October 2003 Value (£): 186,382
EPSRC Research Topic Classifications:
Combinatorial Chemistry
EPSRC Industrial Sector Classifications:
Chemicals Pharmaceuticals and Biotechnology
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
The development of radical based methodologies is usually dependent on the use of chain conditions to minimise by-products and thus limits development of synthetically useful intermolecular processes. The application of heterogeneous (solid-phase) techniques enables such reactions to be carried out under non-chain conditions. Following on from highly promising preliminary work we intend to explore the addition of radicals to a wide range of solid-supported acceptors. Application to the construction of novel glycopeptides will illustrate the potential this methodology has for applications in the production of biologically important molecules.
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Further Information:  
Organisation Website: http://www.sussex.ac.uk