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Details of Grant 

EPSRC Reference: GR/M59945/01
Title: LIGHT SOURCES AND IMAGING SYSTEMS FOR CANCER DETECTION AND TREATMENT
Principal Investigator: Sibbett, Professor W
Other Investigators:
Ferguson, Professor J Allen, Professor J Padgett, Professor M
Cuschieri, Professor Sir A
Researcher Co-Investigators:
Project Partners:
Department: Physics and Astronomy
Organisation: University of St Andrews
Scheme: Standard Research (Pre-FEC)
Starts: 01 April 2000 Ends: 31 March 2002 Value (£): 106,275
EPSRC Research Topic Classifications:
Lasers & Optics
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
The programme described within this application has two distinct areas, both of which will be pursued in a collaborative programme between St Andrews University Physics department and Ninewells Hospital, Dundee University.a) Using the photosensitiser ALA, we will image fluorescence, auto-fluorescence and illumination. The resulting spectroscopic imaging system will be used primarily for detection and characterisation of skin cancers. Basal cell skins carcinomas are similar in nature within the GI tract and therefore act as a useful test-bed for the future design and assessment of endoscopic systems.Using the newly emerging laser diodes based on gallium nitride we will develop an intense fibre-coupled source for excitation of photosensitisers. Addition of red (diode) and green (microchip) lasers will enable a pseudo-white light source to be developed and this affords attractive options for sequential illumination and active colour balancing. This later feature is an especially important and relevant feature of endoscopic imaging procedures of the human body where extended control of the colour balance may be optimised for observing premagligment changes in the skin texture of internal organs.
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Organisation Website: http://www.st-and.ac.uk