| EPSRC Reference: |
GR/M56272/02 |
| Title: |
ROPA: USER-FRIENDLY BUT REACTIVE DIAZOCOMPOUNDS FOR ORGANIC AND POLYMER SYNTHESIS |
| Principal Investigator: |
Aggarwal, Professor VK |
| Other Investigators: |
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| Department: |
Chemistry |
| Organisation: |
University of Bristol |
| Scheme: |
ROPA |
| Starts: |
05 February 2001 |
Ends: |
04 July 2002 |
Value (£): |
56,235
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| EPSRC Research Topic Classifications: |
| Chemical Synthetic Methodology |
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| EPSRC Industrial Sector Classifications: |
| No relevance to Underpinning Sectors |
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Summary on Grant Application Form |
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ROPA - We have recently discovered a novel method for making epoxides from carbonyl compounds using diazocompounds and to make the process user-friendly we have discovered a method of generating these reactive intermediates in situ. This work is ongoing. We now wish to exploit this chemistry in a broad array of additional reactions. These include neutral alkylation of alcohols, direct cyclopropanation of alkenes, non-sulfur ylide mediated epoxidation and aziridination and homologation of ketones. We also propose to use this protocol in a new method for making polyalkyl branched chains in a living polymerisation reaction mediated by organoboranes.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.bris.ac.uk |