EPSRC logo

Details of Grant 

EPSRC Reference: GR/M56272/01
Title: ROPA: USER-FRIENDLY BUT REACTIVE DIAZOCOMPOUNDS FOR ORGANIC AND POLYMER SYNTHESIS
Principal Investigator: Aggarwal, Professor VK
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: University of Sheffield
Scheme: ROPA
Starts: 10 January 2000 Ends: 31 August 2000 Value (£): 91,032
EPSRC Research Topic Classifications:
Chemical Synthetic Methodology
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
ROPA - We have recently discovered a novel method for making epoxides from carbonyl compounds using diazocompounds and to make the process user-friendly we have discovered a method of generating these reactive intermediates in situ. This work is ongoing. We now wish to exploit this chemistry in a broad array of additional reactions. These include neutral alkylation of alcohols, direct cyclopropanation of alkenes, non-sulfur ylide mediated epoxidation and aziridination and homologation of ketones. We also propose to use this protocol in a new method for making polyalkyl branched chains in a living polymerisation reaction mediated by organoboranes.
Key Findings
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Potential use in non-academic contexts
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Impacts
Description This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Summary
Date Materialised
Sectors submitted by the Researcher
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Project URL:  
Further Information:  
Organisation Website: http://www.shef.ac.uk