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Details of Grant 

EPSRC Reference: GR/M40653/01
Title: ROPA: NEW CLASSES OF HYBRID LIGANDS FOR ASYMMETRIC CATALYSIS
Principal Investigator: Page, Professor P
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: Loughborough University
Scheme: ROPA
Starts: 01 April 1999 Ends: 31 March 2001 Value (£): 135,485
EPSRC Research Topic Classifications:
Asymmetric Chemistry
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
Related Grants:
Panel History:  
Summary on Grant Application Form
We have recently demonstrated that hybrid ligands containing chiral sulfoxides can deliver high ees in catalytic asymmetric processes. The objective of this project is to develop understanding of the transition states involved, to design new classes of chiral sulfoxide-containing hybrid ligands, to investigate their use in asymmetric catalysis, and to correlate their activity in catalysis with their structures and reactivity. The ligands will be applied to asymmetric homogeneous catalysis of organic reactions, principally allylic substitution, conjugate addition to enones, and epoxidation. The project falls within both the Chemical Synthesis and Catalysis activities of the EPSRC Chemistry Programme Response to Foresight.
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Organisation Website: http://www.lboro.ac.uk