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Details of Grant 

EPSRC Reference: GR/M07243/02
Title: FLOW LIMITATION AND SELF-EXCITED OSCILLATIONS IN COLLAPSIBLE CHANNELS
Principal Investigator: Luo, Professor X
Other Investigators:
Pedley, Professor TJ
Researcher Co-Investigators:
Project Partners:
Department: Mechanical Engineering
Organisation: University of Sheffield
Scheme: Standard Research (Pre-FEC)
Starts: 01 May 2000 Ends: 30 September 2002 Value (£): 89,063
EPSRC Research Topic Classifications:
Medical science & disease
EPSRC Industrial Sector Classifications:
Healthcare
Related Grants:
Panel History:  
Summary on Grant Application Form
One of the principal questions of interest in forced expiration from the lungs is whether there is a causal relationship between wheezing (a kind of oscillation) and flow limitation ie the phenomenon that increasing a large expiratory driving pressure does not lead to an increase in flow rate on account of airway collapse. The proposed research will look into the self-excited oscillations found previously in the two dimensional study and answer the question if there is a causal link between the self-excited oscillations and flow limitation. This will be the first time that collapse and flutter will have been examined together, self-consistently, in the same model problem. In order to better interpret and understand the numerical results and the mechanisms, a direct comparison with a channel flow experimental results that has been designed for the purpose will be carried out.EngProg\
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Organisation Website: http://www.shef.ac.uk