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Details of Grant 

EPSRC Reference: GR/L82755/01
Title: THE EFFECT OF CSF ON CEREBRAL IMAGE RECONSTRUCTION USING OPTICAL TOMOGRAPHY
Principal Investigator: Delpy, Professor DT
Other Investigators:
Researcher Co-Investigators:
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Department: Medical Physics and Biomedical Eng
Organisation: UCL
Scheme: Standard Research (Pre-FEC)
Starts: 01 August 1998 Ends: 31 July 2001 Value (£): 158,471
EPSRC Research Topic Classifications:
Instrumentation Eng. & Dev.
EPSRC Industrial Sector Classifications:
No relevance to Underpinning Sectors
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Summary on Grant Application Form
The project is centred around the development of a methodology for reconstructing images from near-infrared spectroscopy data for the diagnosis of hypoxic ischaemic injury in newborn infacts. One requirement of such an imaging technique is a fast and accurate model of light propagation in tissue. Current models are limited to two dimensions, due to memory limitations and are only valid in scattering regions due to assumptions made in the model.Previous experimental and theoretical work carried out at UCL has shown that the presence of the non scattering CFS layer around the brain is likely to have a significant effect on the propagation of NIR light through the head. The work proposed in this application will investigate the effect of this CSF layer on the problem of NIR image reconstruction and attempt to improve the modelling of light transport in inhomogeneous objects with non scattering regions in order to include this effect in image reconstructions of the neonatal head. The project will also investigate the potential of reducing the memory requirements of the current model by using logarithmic interpolation in the elements of the finite element model of light transport, which would allow the possibility of more accurate 3D modelling.
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