| EPSRC Reference: |
GR/L71933/01 |
| Title: |
TEMPLATE-DIRECTED POLYMERIZATION OF NUCLEOSIDE SUBSTITITED ACRYLIC ESTERS |
| Principal Investigator: |
Marsh, Dr A |
| Other Investigators: |
|
| Researcher Co-Investigators: |
|
| Project Partners: |
|
| Department: |
Chemistry |
| Organisation: |
University of Warwick |
| Scheme: |
Standard Research (Pre-FEC) |
| Starts: |
11 January 1999 |
Ends: |
10 July 2002 |
Value (£): |
54,283
|
| EPSRC Research Topic Classifications: |
| Materials Synthesis & Growth |
|
|
| EPSRC Industrial Sector Classifications: |
| Chemicals |
Pharmaceuticals and Biotechnology |
| No relevance to Underpinning Sectors |
|
|
| Related Grants: |
|
| Panel History: |
|
|
Summary on Grant Application Form |
|
We aim to develop a template assisted polymerisation of acrylic substituted nucleosides to enable the controlled synthesis of novel biopolymer mimics. the conditions under which the polymerisation will be carried out will promote the formation of specific hydrogen bonding interactions between complimentary nucleobases. the catalyst used is recently developed and allows excellent control of polydispersity and number molecular weight. Kinetic analysis of the polymerisation will be used to characterise the process; structural analysis of the polymers using nmr and mass spectrometry will enable detail such as chemical sequence copolymers to be elucidated. The novel biopolymers will be investigated for their interaction with nucleic acids.
|
|
Key Findings |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Potential use in non-academic contexts |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
|
Impacts |
|
| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
|
| Date Materialised |
|
|
|
|
Sectors submitted by the Researcher |
|
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
|
| Project URL: |
|
| Further Information: |
|
| Organisation Website: |
http://www.warwick.ac.uk |