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EPSRC Reference: GR/L17139/01
Title: SPATIO-TEMPORAL COMPLEXITY RE-ENTRANT ACTIVITY MODELS CARDIAC TISSUE DURING HUMAN VENTRICULAR FIBRILLATION
Principal Investigator: Holden, Professor A
Other Investigators:
Broomhead, Professor D
Researcher Co-Investigators:
Project Partners:
Freeman Group of Hospitals NHS Trust
Department: School of Biomedical Sciences
Organisation: University of Leeds
Scheme: Standard Research (Pre-FEC)
Starts: 01 November 1996 Ends: 31 August 1998 Value (£): 45,601
EPSRC Research Topic Classifications:
Non-linear Systems Mathematics
EPSRC Industrial Sector Classifications:
R&D
Related Grants:
Panel History:  
Summary on Grant Application Form
Ventricular fibrillation is produced by irregular spatio-temporal propagation in heart muscle. We aim to quantify this irregularity using both computer simulations and clinical recordings of ventricular fibrillation, and use measures we obtain to prospectively distinguish between self-terminating and persistent (lethal unless defibrillated) ventricular fibrillation. We expect to be able to classify episodes of fibrillations in terms of different nonlinear wave behaviours of excitable media.
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Organisation Website: http://www.leeds.ac.uk