EPSRC logo

Details of Grant 

EPSRC Reference: GR/K95901/01
Title: TOTAL SYNTHESIS OF BIOLOGICALLY ACTIVE HETEROCYCLIC NATURAL PRODUCTS
Principal Investigator: Thomas, Professor EJ
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Chemistry
Organisation: Victoria University of Manchester, The
Scheme: Standard Research (Pre-FEC)
Starts: 01 October 1996 Ends: 31 January 1999 Value (£): 94,288
EPSRC Research Topic Classifications:
Biological & Medicinal Chem.
EPSRC Industrial Sector Classifications:
Related Grants:
Panel History:  
Summary on Grant Application Form
It is proposed to complete a total synthesis of the macrocyclic antibiotic lankacidin C. key steps will be the stereoselective acylation of an azetidinone, an intermolecular transacylation of the azetidinone to give the six-membered lactone fragment, and the macrocylisation step. Once this synthesis is complete, we will continue on a different synthesis, namely a synthesis of the insecticidal alkaloid stemofoline.
Key Findings
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Potential use in non-academic contexts
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Impacts
Description This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Summary
Date Materialised
Sectors submitted by the Researcher
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
Project URL:  
Further Information:  
Organisation Website: