| EPSRC Reference: |
GR/K91729/01 |
| Title: |
A NOVEL CHIRALITY RELAY AND AMPLIFICATION METHODOLOGY FOR THE ASYMMETRIC SYNTHESIS OF AMINO ACIDS.ROPA. |
| Principal Investigator: |
Davies, Professor SG |
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| Department: |
Oxford Chemistry |
| Organisation: |
University of Oxford |
| Scheme: |
ROPA |
| Starts: |
01 October 1996 |
Ends: |
30 September 1998 |
Value (£): |
93,478
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Summary on Grant Application Form |
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We have recently developed a new crystalline auxiliary which can be used for the asymmetric synthesis of a-amino acids on an multigramme scale. We wish to explore the use of this auxiliary for preparing both enantiomers of a-amino acids from the same homochiral auxiliary and use this protocol where the quantity of a-amino acid is effectively doubled while a novel Michael addition approach will generate homochiral a, b-substituted a-amino acids in a one pot reaction.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.ox.ac.uk |