| EPSRC Reference: |
GR/K89719/01 |
| Title: |
ROPA: OXYMINIUM IONS. NEW VERSATILE, REACTIVE INTERM- EDIATES FOR HETEROCYCLE SYNTHESIS |
| Principal Investigator: |
Grigg, Professor R |
| Other Investigators: |
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| Department: |
Sch of Chemistry |
| Organisation: |
University of Leeds |
| Scheme: |
ROPA |
| Starts: |
01 October 1996 |
Ends: |
30 September 1999 |
Value (£): |
55,740
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Summary on Grant Application Form |
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The chemistry of oxyiminium ions [R1R2C=N(R3)OR4], a new type of reactive intermediate readily accessible from oxime ethers, olefins and electrophiles, will be developed to provide (1) a range of electrophiles/electrophilic metal catalysts that induce oxyiminium ion formation and provide handles facilitating further synthetic manipulation (2) fragmentable and non-fragmentable OR groups with additional reactive functionality which facilitates heterocyclic ring forming processes (3) oxyiminium analogues of the Mannich Reaction aza-Cope, combined aza-Cope-oxyiminium aldol etc (4) chiral induction via chiral OR groups and chiral electrophiles/catalysts.
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Key Findings |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Potential use in non-academic contexts |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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Impacts |
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| Description |
This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk |
| Summary |
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| Date Materialised |
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Sectors submitted by the Researcher |
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This information can now be found on Gateway to Research (GtR) http://gtr.rcuk.ac.uk
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| Project URL: |
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| Further Information: |
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| Organisation Website: |
http://www.leeds.ac.uk |