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Details of Grant 

EPSRC Reference: GR/K62354/01
Title: PALLADIUM CATALYSED MOLECULAR SWITCHING CASCADES
Principal Investigator: Grigg, Professor R
Other Investigators:
Researcher Co-Investigators:
Project Partners:
Department: Sch of Chemistry
Organisation: University of Leeds
Scheme: ROPA
Starts: 01 October 1995 Ends: 30 June 1999 Value (£): 150,398
EPSRC Research Topic Classifications:
Catalysis & Applied Catalysis
EPSRC Industrial Sector Classifications:
Chemicals
Related Grants:
Panel History:  
Summary on Grant Application Form
Multicomponent palladium catalysed cascade process with minimum or zero waste ( high or total \tom economy), employing a starter species, 1-n relay switch components, and a capping reagent, will be developed. The relative rates of incorperation of relay switch components will be ascertained. Initiation procedures (oxidative-addition, HPdX addition to akynes, ho) will be developed and the scope of the capping reagents explored. The new process will be applied to formation of all ring motifs (fused, spiro, bridged), relevant to chemical industry, and chiral induction studied.
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Organisation Website: http://www.leeds.ac.uk